Creative Commons License

Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.

Course Instructor

Erika Kancler

Date of Graduation

Fall 12-14-2018


Objective: Assess the long-term outcomes including mortality, revascularization and myocardial infarction events to determine whether off-pump CABG is more effective for patients compared to on-pump CABG procedures.

Methods: Studies were found using PubMed with the search term, “on and off pump CABG” which yielded 1736 studies. After assessing for records within 5 years the search was narrowed to 370 articles and then down to 353 because some articles were not available in full-text. Our search was then divided into first looking at randomized control trials and meta-analysis availability from the 353 articles meeting our criteria. After narrowing our search for only randomized control trials, we were left with 47 articles. We lastly went back to the 353 articles and narrowed that search to only available meta-analysis which gave us 27 options. The final studies were chosen based on their relation to our clinical question.

Results: Studies show that there are no significant differences in the number of events sustained (or occurring) after both the off-pump CABG and on-pump CABG procedures. This was evident by results that varied between the three studies in which all percentages were close in number of events per population.

Conclusion: In regard to deciding whether to perform on-pump CABG or off-pump CABG, the physician and patient need to make a joint decision based on the patient’s comorbidities and the physician’s experience as a surgeon. There is not conclusive evidence that one approach is more effective than the other.

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