Effectiveness of the Mediterranean Diet and Lifetime Risk Reduction of Alzheimer Disease
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Dr. Abby Massey
Date of Graduation
Objective: Determine if a significant clinical correlation exists between adherence to a Mediterranean Diet and decreased lifetime risk of Alzheimer disease in non-demented adults 60-80 years old. Design: Systematic literature review. Methods: Searches were done in PubMed using MESH terms cognitive decline, low fat diet, Mediterranean, and prevention; in PubMed the following limits and terms were applied: published in the last 12 years, humans, English; excluding meta-analyses and systematic reviews. Results: The systematic review yielded four studies: a randomized control trial completed by C. Valls-Pedret et al. (2015), two prospective cohort studies by C. Feart et al. (2009) and N. Scarmeas et al. (2006), and a cross-sectional observational study by R. Roberts et al. (2010). Conclusion: The studies evaluated by this paper find a significant correlation between a high-adherence to the entire Mediterranean Diet and decreased incidence of Alzheimer Disease and cognitive decline, though further research is recommended.
Huesgen E. Effectiveness of the Mediterranean Diet and Lifetime Risk Reduction of Alzheimer Disease. JMU Scholarly Commons Physician Assistant Capstones. https://commons.lib.jmu.edu/pacapstones/41/. Published December 11, 2019.