Creative Commons License

Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.

Date of Graduation

Spring 2011

Document Type


Degree Name

Master of Science (MS)


Department of Kinesiology


The purpose of this investigation was to examine the potential effects of SR2W-1 supplementation on cycling performance, central fatigue, and a variety of physiological parameters, including blood lactate, blood pH, heart rate (HR), rating of perceived exertion (RPE), oxygen consumption (VO2), expired ventilation (VE), and respiratory exchange ratio (RER). Methods: Five recreational cyclists (38 ± 8 yr, 168.4 ± 4.3 cm, 68.8 ± 5.6 kg, and 54.4 ± 2.6 mL/kg/min) performed 20-min of steady-state cycling (~85% VO2max) followed by three 1-min high intensity intervals at VO2max with 30-sec active recovery periods at 100 W, 15-min passive recovery period, and a ride to fatigue (or < 50 RPM) at VO2max. Subjects were randomly assigned to receive either 1000mg/d of SR2W-1 (EXP) or 1000mg/d placebo (PLA). The supplement was distributed in a double-blind, crossover fashion. The twenty-one day supplementation periods were separated by a 14-day “washout” period. Change-scores from pre- to post- supplementation were calculated for all parameters, under both PLA and EXP conditions. Wilcoxon Signed-Rank Tests were utilized to compare change-scores between PLA and EXP conditions. Results: There were no differences between PLA and EXP for any of the dependent variables; however several variables approached significance (p < 0.1). Specifically blood glucose levels, HR and ventilation increased to a greater extent with EXP, compared to PLA throughout the 20-min ride and high intensity intervals. Conclusion: Notwithstanding the small sample size, 3 weeks of herbal supplementation (SR2W-1) does not appear to aid in cycling performance, attenuate skeletal muscle fatigue, or modify the general physiological responses to exercise.



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