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Date of Graduation
Master of Science (MS)
Department of Kinesiology
The purpose of this investigation was to examine the potential effects of SR2W-1 supplementation on cycling performance, central fatigue, and a variety of physiological parameters, including blood lactate, blood pH, heart rate (HR), rating of perceived exertion (RPE), oxygen consumption (VO2), expired ventilation (VE), and respiratory exchange ratio (RER). Methods: Five recreational cyclists (38 ± 8 yr, 168.4 ± 4.3 cm, 68.8 ± 5.6 kg, and 54.4 ± 2.6 mL/kg/min) performed 20-min of steady-state cycling (~85% VO2max) followed by three 1-min high intensity intervals at VO2max with 30-sec active recovery periods at 100 W, 15-min passive recovery period, and a ride to fatigue (or < 50 RPM) at VO2max. Subjects were randomly assigned to receive either 1000mg/d of SR2W-1 (EXP) or 1000mg/d placebo (PLA). The supplement was distributed in a double-blind, crossover fashion. The twenty-one day supplementation periods were separated by a 14-day “washout” period. Change-scores from pre- to post- supplementation were calculated for all parameters, under both PLA and EXP conditions. Wilcoxon Signed-Rank Tests were utilized to compare change-scores between PLA and EXP conditions. Results: There were no differences between PLA and EXP for any of the dependent variables; however several variables approached significance (p < 0.1). Specifically blood glucose levels, HR and ventilation increased to a greater extent with EXP, compared to PLA throughout the 20-min ride and high intensity intervals. Conclusion: Notwithstanding the small sample size, 3 weeks of herbal supplementation (SR2W-1) does not appear to aid in cycling performance, attenuate skeletal muscle fatigue, or modify the general physiological responses to exercise.
Ata, Tara Ali, "The effects of sr2w-1 supplementation on cycling performance and muscle fatigue" (2011). Masters Theses. 137.