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Date of Graduation
TBI = Traumatic Brain Injury
Glasgow Outcome Scale = GOS
Glasgow Outcome Scale Extended = GOSE
Objective: To determine whether hypothermia induction improves long-term morbidity and mortality in patients with severe traumatic brain injury
Methods: A search was conducted using PubMed database and the search terms “induced hypothermia” and “traumatic brain injury”. Studies were excluded if the publication dates were over 10 years old, children were the population being studied, and the researchers were looking at other independent variables.
Results: The results from all three randomized control trials showed that the induction of hypothermia did not show effectiveness in the treatment of patients with a TBI compared to patients in the normothermia groups. However, one of the three studies did show better outcomes in patients with intracranial hematomas that underwent surgery and were also maintained at a hypothermic body temperature compared to a normothermic body temperature. This result deserves further research to determine whether this treatment could be applied to the general population of patients with intracranial hematomas.
Conclusion: At this time, it is not recommended to induce hypothermia in patients with a traumatic brain injury because it does not improve long-term morbidity and mortality but more research should be conducted to determine whether this treatment strategy could be of use in the future.
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