Creative Commons License

Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.

Course Instructor

Abby Massey

Capstone Semester

Fall 2021

Date of Graduation



Objective: To determine whether obese and morbidly obese patients aged 18-75 with a lower baseline BMI (BMI 30-39.9 kg/m2) who received an intragastric balloon (IGB), have a higher percentage of total body weight loss (%TBWL) and percentage of excess weight loss (%EWL) compared to those with a higher baseline BMI (BMI > 40 kg/m2). Secondary objective was to ascertain whether gender and age are also predictors of weight loss outcomes following an IGB procedure.

Design: Systematic literature review

Methods: Literature searches of PubMed and SpringerLink were conducted using the search terms: “intragastric balloon, weight loss, and “BMI” and then limited to publications within the years 2010-2020. The following limits were used: study available in the English language, patients 18 years or older, results stratification by BMI, and study designs that were randomized control trials, cohorts, or case controls followed for six months total. Results: Using the keywords mentioned above in PubMed and SpringerLink, three studies met the inclusion and exclusion criteria: a prospective cohort study by Diab et al., a case control study by Lopez-Nava et al., and a prospective cohort study Lecumberri, et al.

Conclusion: No significant difference in %TBWL was found in all the studies reviewed. All three studies concluded that gender had little difference in weight loss outcomes, however there was variability in conclusions on age and baseline BMI. Two out of three studies ascertained that younger patients and patients with lower baseline BMI show greater %EWL, concluding that baseline BMI and age can be used as predictors of IGB weight loss outcomes.

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