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Date of Graduation
12-12-2025
Semester of Graduation
Fall
Abstract
Objective: To assess the efficacy of combination therapy of platelet-rich plasma (PRP) and topical 5% minoxidil compared to topical 5% minoxidil alone in androgenetic alopecia (AGA). Methods: A PubMed search using the term “PRP hair” was conducted. The following criteria were used for the search: published in the last 10 years, randomized controlled trials, clinical trials, free full text, and full text. Three articles that met these criteria were chosen for systematic review. Results: In all three studies, the combination of PRP with topical 5% minoxidil had increased hair density and higher patient satisfaction compared to topical minoxidil alone. Conclusion: PRP combined with topical 5% minoxidil improves hair density and patient satisfaction compared to PRP alone in individuals with AGA. However, PRP is currently not FDA-approved for AGA and is considered an “off-label” treatment. Further research is needed to determine long-term efficacy of PRP with topical 5% minoxidil and whether maintenance therapy is required following the initial treatment course.
Recommended Citation
Owens and Son. Comparison of the combination of PRP and topical minoxidil to topical minoxidil alone on androgenetic alopecia. Published December 10, 2025.
