Utility of Bariatric Surgery in the Remission of Type 2 Diabetes Mellitus

Faculty Advisor Name

Abby Massey

Department

Department of Health Professions

Description

Objective: Assess whether bariatric surgery is more effective than lifestyle modification and medication in the long-term reduction of hemoglobin A1c (HbA1c) and fasting plasma glucose among obese adults with type 2 diabetes mellitus. Design: Systematic literature review. Methods: A PubMed search was performed utilizing the terms bariatric surgery, type 2 diabetes and remission. In PubMed the following limits and terms were used: published in the last 10 years, humans, full text, clinical trial, randomized control trial, and English. Results: An analysis of three randomized control trials (RCTs) supports bariatric surgery as a modality to induce the remission of type 2 diabetes mellitus (T2DM) in overweight or obese adults, however the results show a decline in success after the first 12 months after surgery. Conclusion: While shown to be beneficial in the initial 12-month period, the long-term data does not support the utility of bariatric surgery alone in the induction of T2DM.

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Utility of Bariatric Surgery in the Remission of Type 2 Diabetes Mellitus

Objective: Assess whether bariatric surgery is more effective than lifestyle modification and medication in the long-term reduction of hemoglobin A1c (HbA1c) and fasting plasma glucose among obese adults with type 2 diabetes mellitus. Design: Systematic literature review. Methods: A PubMed search was performed utilizing the terms bariatric surgery, type 2 diabetes and remission. In PubMed the following limits and terms were used: published in the last 10 years, humans, full text, clinical trial, randomized control trial, and English. Results: An analysis of three randomized control trials (RCTs) supports bariatric surgery as a modality to induce the remission of type 2 diabetes mellitus (T2DM) in overweight or obese adults, however the results show a decline in success after the first 12 months after surgery. Conclusion: While shown to be beneficial in the initial 12-month period, the long-term data does not support the utility of bariatric surgery alone in the induction of T2DM.