Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.
Date of Award
Bachelor of Science (BS)
Department of Biology
Corey L. Cleland
There have been numerous studies in non-human animals on the effect of stimulus location on the NWR and at least a few studies that address the role of initial posture. However, all of these studies were conducted in anesthetized, decerebrated, or spinalized mammals. Since descending modulation and long loop reflexes may influence the NWR, the anesthetized spinalized/decerebrated animal may not be an adequate model of normal animals. Therefore, the primary aim of this study was to determine the effect of the stimulus location and initial paw position on the direction and magnitude of the nociceptive withdrawal response to heat stimulus delivered to various locations on the plantar surface of the paw of intact, unanesthetized rats. Based on previous research, it was hypothesized that stimulus location and initial position of the paw would both have an effect on the NWR.
Seamon, Kimberly, "Rat hind limb nociceptive withdrawal response depends on initial paw position but not stimulus location" (2015). Senior Honors Projects, 2010-current. 128.