Senior Honors Projects, 2010-2019

Creative Commons License

Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.

Date of Graduation

Spring 2019

Document Type


Degree Name

Bachelor of Science (BS)


Department of Kinesiology


Christopher J. Womack

Stephanie P. Kurti

Jessica G. Irons


Purpose: To test the effect of body composition, cardiorespiratory fitness, and physical activity levels on serum gamma-glutamyltransferase (GGT) among college students who consume alcohol. Methods: Seven male and nine female subjects over 21 years old completed the Alcohol Use Disorders Identification (AUDIT), a maximal treadmill test to measure maximal oxygen uptake (VO2max), a DEXA scan for body fat percentage, and a venous blood draw for serum GGT. In addition, subjects were assessed with respect to average daily moderate-to-vigorous physical activity (MVPA) via continuously worn (while awake) accelerometer for one week. Subjects were grouped based on AUDIT scores [ > 8= high alcohol intake (n = 9); < 8 = low alcohol intake (n = 7)] and compared with respect to outcome variables using a series of independent t-test. Correlations between serum GGT and other outcome variables were established using Pearson correlation coefficients in the higher AUDIT group. Results: No significant differences were found between lower and higher AUDIT groups with respect to average (± SD) VO2max (62.37 ± 11.09 vs. 62.02 ± 5.16 ml/kg FFM/min), average MVPA (45.15 ± 23.55 vs. 49.99 ± 16.82 minutes/day), body fat % (26.7 ± 8.0 vs. 22.9 ± 4.1 %) and serum GGT (13.93 ± 1.96 vs. 15.94 ± 3.33 U/L). For the higher AUDIT group, there was no correlation between serum GGT and VO2max or body fat %, but there was a trend towards a negative correlation between average daily MVPA and serum GGT (r = -0.65, p = 0.06). Conclusion: Findings suggest that chronic physical activity has a positive impact on serum GGT in individuals with high AUDIT scores. These findings warrant further investigation with larger sample size.



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