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ORCID
https://orcid.org/0009-0002-0025-6201
Date of Graduation
8-1-2025
Semester of Graduation
Summer
Degree Name
Master of Arts (MA)
Department
Department of Graduate Psychology
First Advisor
Jessica G. Irons
Abstract
The purpose of the current study was to assess the acute effects of tetrahydrocannabivarin (THCV) on appetite. Participants (N = 28) experienced 12.5 mg THCV, 25mg THCV, and placebo in counterbalanced order across three, 3-hr experimental sessions. Following baseline procedures, participants consumed THCV or placebo and completed self-report measures every 30 minutes. A series of repeated measures factorial ANOVAs were conducted to examine potential differences in study outcomes across THCV dosing conditions as well as within session (i.e., baseline, every 30 minutes after dosing (5), end of session) with respect to self-reported hunger, mood, and perceived drug effects (e.g., happiness, anxiety). Study results suggest that THCV, in the current study doses, is distinguishable from placebo but may yield no or small effects related to appetite, mood, or perceived drug effects. Due to high costs and limited accessibility of treatments for appetite-related disorders, further research is necessary to understand the potential effects of THCV on appetite and related variables across a greater range of doses and among clinical samples who experience appetite-related conditions.
